Carboxylic acids and derivatives
Medchemexpress LLC Adenosine 5'-(α,β-methylene)diphosphate triammonium | 3768-14-7 | 99.9% | 476.32 | 10 MG
MethADP (Adenosine 5'-(α,β-methylene)diphosphate) triammonium is a CD73 inhibitor, and it can be utilized for research into the ATP-adenosine pathway.
- Functions as a CD73 inhibitor.
- Useful for research concerning the ATP-adenosine pathway.
- Inhibits 5'-AMP induced adenosine formation in A498 cells at concentrations of 20 and 100 μmol/L.
Medchemexpress LLC Sodium citrate monobasic | 18996-35-5 | 98.0% | 214.11 | 500 G
Sodium citrate monobasic is a natural preservative and food tartness enhancer. It induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. It can cause oxidative damage of the liver by decreasing antioxidative enzyme activities. It is also an acidulant, emulsifier, sequestrant, and buffering agent used across many industries.
- Solid appearance
- White to off-white color
- Store at room temperature, keep dry and cool
- In solvent, store at -80°C for 1 year or -20°C for 6 months
Medchemexpress LLC Pacritinib citrate | 1228923-42-9 | 99.7% | 664.70 | 5 MG
Pacritinib citrate is a potent inhibitor of both wild-type JAK2 (IC50=23 nM) and JAK2V617F mutant (IC50=19 nM). It also inhibits FLT3 (IC50=22 nM) and its mutant FLT3D835Y (IC50=6 nM). Pacritinib citrate can be used for the research of acute myeloid leukemia (AML) and myelofibrosis (MF).
- Potent inhibitor of wild-type JAK2 (IC50=23 nM)
- Potent inhibitor of JAK2V617F mutant (IC50=19 nM)
- Inhibits FLT3 (IC50=22 nM)
- Inhibits FLT3D835Y mutant (IC50=6 nM)
- Can be used for the research of acute myeloid leukemia (AML)
- Can be used for the research of myelofibrosis (MF)